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Cake day: June 16th, 2023

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  • I’d add on that the expectation in an individualist society like the US is to become independent and move out. Those ideas are used synonymously in a lot of contexts. Someone who hasn’t moved out can be seen as lacking independence. Of course that isn’t necessarily true, but it’s the perception.

    For a young person growing up with these ideas as the standard, there can be a certain safety in forgoing that independence. That was my situation for years, where I was financially independent, but moved back home after my roommates moved away. I was in my mid twenties before I moved out for good.




  • • Enter The Matrix [Ties Into The Matrix Resurrections]

    • Avatar: Frontiers Of Pandora [Co-Exists With The Avatar Movies]

    • Ghostbusters: The Video Game [Acts As A Sequel To Ghostbusters II]

    • Marvel’s Spider-Man (2018) [Exists In The Spider-Verse]

    • The Thing [Takes The Mystery Out Of The Movie’s Ending]

    • Saw: The Video Game [Saw’s Creators Contributed To The Game]

    • Mad Max [Introduced Furiosa’s Main Villain]

    • The Lord Of The Rings Online [Expands The World Of Middle-Earth]

    • Star Wars Jedi: Survivor [Part Of The Star Wars Timeline]

    • Kingdom Hearts 3 [The Toy Story world is meant to take place before Toy Story 3 in the canon timeline of the movies.]

    Some of these are a stretch, imo



  • From the article, not in OP’s summary:

    In 2007, the FDA published guidance on regulatory limits for DNA vaccines in the Guidance for Industry: Considerations for Plasmid DNA Vaccines for Infectious Disease Indications (Guidance for Industry). In this Guidance for Industry, the FDA outlines important considerations for vaccines that use novel methods of delivery regarding DNA integration, specifically:

    • DNA integration could theoretically impact a human’s oncogenes – the genes which can transform a healthy cell into a cancerous cell.

    • DNA integration may result in chromosomal instability.

    • The Guidance for Industry discusses biodistribution of DNA vaccines and how such integration could affect unintended parts of the body including blood, heart, brain, liver, kidney, bone marrow, ovaries/testes, lung, draining lymph nodes, spleen, the site of administration and subcutis at injection site.

    On December 14, 2023, the FDA provided a written response providing no evidence that DNA integration assessments have been conducted to address risks outlined by the FDA themselves in 2007. Based on the FDA’s recognition of unique risks posed by DNA integration, the efficacy of the COVID-19 mRNA vaccine’s lipid nanoparticle delivery system, and the presence of DNA fragments in these vaccines, it is essential to human health to assess the risks of contaminant DNA integration into human DNA. The FDA has provided no evidence that these risks have been assessed to ensure safety. As such, Florida State Surgeon General Dr. Joseph A. Ladapo has released the following statement:

    “The FDA’s response does not provide data or evidence that the DNA integration assessments they recommended themselves have been performed. Instead, they pointed to genotoxicity studies – which are inadequate assessments for DNA integration risk. In addition, they obfuscated the difference between the SV40 promoter/enhancer and SV40 proteins, two elements that are distinct.

    DNA integration poses a unique and elevated risk to human health and to the integrity of the human genome, including the risk that DNA integrated into sperm or egg gametes could be passed onto offspring of mRNA COVID-19 vaccine recipients. If the risks of DNA integration have not been assessed for mRNA COVID-19 vaccines, these vaccines are not appropriate for use in human beings.

    Providers concerned about patient health risks associated with COVID-19 should prioritize patient access to non-mRNA COVID-19 vaccines and treatment. It is my hope that, in regard to COVID-19, the FDA will one day seriously consider its regulatory responsibility to protect human health, including the integrity of the human genome.”










  • To quote the video this post is about, I often see this happen:

    “wow, these rules are so robust!” followed by, “wow… these rules are so… robust.”

    Pathfinder is neat, I play in three 2e campaigns. I prefer 5e, and that’s okay. Personally, I think the rules get in the way of the fun for pf2e. I still have fun, I would just have more fun in a less rule-heavy game.

    I shy away from saying 5e is better, because I know many people who prefer pf2e, just like I and many others prefer 5e, or savage worlds, or shadow dark. Different games will attract different players, and sometimes those players who like different things play together. When this happens, compromise happens in order to play the same game. The hobby is better served by us looking for ways to compromise, rather than divide.



  • As if most of the feats in pf2e aren’t? I enjoy pathfinder for what it is, and there definitely some things I like more than 5e. Pathfinder has more feats, and has more good feats, but also more underwhelming feats in my opinion. How many characters take abberation kinship?

    The difference is that pf2e expexts you to have several feats by the time you’re even level 4, while 5e expects you to (optionally) have 1.




  • Linuto@lemmy.worldto3DPrinting@lemmy.world[SOLVED] Extruder clicking
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    10 months ago

    Like others are saying, probably a clogged nozzle. However, I want to say I just went through this myself and it was not a clogged nozzle. At temperature, I could put light pressure on the filament with my hand and it would come out smoothly, no clog. It can also be that your nozzle is too close to the print bed. In my case, it would do this even when suspended in the air, so that was not the issue.

    I upgraded to a metal extruder, and no longer have this issue.

    Despite what most people say, sometimes parts are the problem. This other commenter explained better.