An increasing number of studies are showing that marijuana may not be so harmless after all.

In two new studies, to be presented later this month at the American Heart Association (AHA) Scientific Sessions 2023, researchers found that regular marijuana use increased the risk of heart attack, stroke or heart failure — even after factors like type 2 diabetes, high blood pressure and obesity were taken into account.

“Prior research shows links between marijuana use and cardiovascular disease like coronary artery disease, heart failure and atrial fibrillation, which is known to cause heart failure,” lead study author Yakubu Bene-Alhasan, M.D., MPH, a resident physician at Medstar Health in Baltimore, said in a statement. “Marijuana use isn’t without its health concerns, and our study provides more data linking its use to cardiovascular conditions.”

  • GONADS125@lemmy.world
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    8 months ago

    Important to note that the population of the study all had a history of cardiovascular health issues, and were not representative of the rest of the population.

    Also important to note is the failure to assess a distinction between combustion and non-combustion consumption.

    Combusting marijuana results in particulates, carcinogens [1], lack of oxygen, and off-gasses benzene. [2] These are very important factors to control for, and this distinction was not addressed at all.

    Definitely in need of further studies on the topic. This is an interesting area to explore, but this study falls a little flat in addressing any causation.

  • Chainweasel@lemmy.world
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    8 months ago

    Funny how both studies focus on smoking though, it’s almost as if inhaling smoke isn’t healthy 🤯.

    • kromem@lemmy.world
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      8 months ago

      My biggest complaint with most cannabis research is the failure to subgroup results by delivery mechanism.

      Do people that don’t smoke at all but use oral cannabis have higher heart complication risks, and if so how much are they elevated compared to the norm and compared to the subgroups that smoke?

      But no, it’s usually just catchy headlines about “cannabis correlated with X” when I get the feeling many times it’s really “smoking things correlated with X.”

          • Burn_The_Right@lemmy.world
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            8 months ago

            Except when it’s a study that completely ignores very obvious alternative causes for its outcome. In that case, it’s reasonable to suspect malice.

    • Kbobabob@lemmy.world
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      8 months ago

      Funny how both studies focus on smoking though

      But it didn’t and even says so… I’d take this with a grain of salt. It’s not very scientific IMO.

      A limitation of the study is that it relied on data that did not specify whether the marijuana was inhaled or eaten. According to researchers, how marijuana is ingested may influence cardiovascular outcomes.

  • alienanimals@lemmy.world
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    8 months ago

    First, fuck the shitty sellout who came up with the clickbait title. Smoking use was linked to those issues, not marijuana.

    Second, are there any studies that show consuming edibles has negative effects?

  • SheeEttin@lemmy.world
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    8 months ago

    I’m on my phone so it’s a pain to try and find the original studies, but I see that in one, they didn’t account for smoking vs eating edibles, and the other seems to have mostly focused on smoking.

    • TWeaK@lemm.ee
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      8 months ago

      No surprise there. My first thought was that this was more correlation than causation - people who take cannabis are more likely to do a range of things that cause heart problems. But you may be onto something with smoking. Smoking breaks things down into all sorts of nasty carbon particulates.

      Not that this rules out cannabis damage to the heart or brain, mind, but the phrase “more study is needed” cannot be emphasised enough.

    • TurboDiesel@lemmy.world
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      8 months ago

      In my experience ingestion route doesn’t make a difference; smoked or eaten, marijuana definitely makes my heart beat significantly faster and more irregularly and spikes my blood pressure.

      • bassomitron@lemmy.world
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        8 months ago

        That sounds like an improper dosage issue to me, tbh. I only use a dry herb vape occasionally (maybe once every couple of days, sometimes I go weeks without it), but some strains with higher potency effect me like how you describe. However, I started getting super light strains (<10% THC) from the dispensary and it made a huge difference. Also, if I only take like one puff, I still get a relaxing buzz but none of that heart racing you speak of.

        Anywho, worth considering.

      • holycrapwtfatheism@kbin.social
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        8 months ago

        6ish years of pretty decent on/off use only edibles and vape. My BP actually drops during use (I monitor due to previous HBP issues). This is going to be like any medicinal use, everyone will have different sides/severities.

      • kromem@lemmy.world
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        8 months ago

        It definitely makes a difference.

        Given the extensive research around smoking and heart health, a ‘placebo’ group that was regularly smoking wood chips in blunts (or any kind of burnt vegetation) would be expected to have heart complications.

        That smoking isn’t the only factor here is probable, but that it isn’t a factor at all is extremely unlikely.

        Which is why research really needs to break out subgroups based on delivery mechanism.

      • GONADS125@lemmy.world
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        8 months ago

        Even if BPM is affected by non-combustion, it doesn’t mean the carcinogens, particulates, lack of oxygen, and benzene from combustion couldn’t play a key role in the cardiovascular health problems in the studies.

      • DaftWiz@lemmy.world
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        8 months ago

        IMO, an elevated heart rate after smoking could be a result of some underlying form of anxiety as well. And some strains seem to aggravate the situation.

    • PeterPoopshit@lemmy.world
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      8 months ago

      All the new marijuana hate junk science articles will stop coming along in such numbers after Ohio’s election. Just watch.

  • Otakulad@lemmy.world
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    8 months ago

    So does tobacco use. If people are going to use this study as a reason to ban marijuana, then shouldn’t we ban tobacco as well?

    • Square Singer@feddit.de
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      8 months ago

      Yes. From a medical standpoint tobacco is terrible, hence regulations make it more difficult to smoke all over the world.

      The issue is that there are so many smokers, that they are a force to be reconned with.

      If tobacco was introduced now, it would probably be on the same legal status as meth. Same with alcohol.

    • sizzler@lemmy.world
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      8 months ago

      Uk just did today and your comment has made me realise cannabis will never be legalised in the uk

  • Pat_Riot@lemmy.today
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    8 months ago

    Given all of the things we as humans consume that are known to be bad for us, (here’s looking at you processed sugar) I’m in the who fucking cares camp. Let me burn a doobie and be mellow. I am definitely not trying to live forever.

      • Pat_Riot@lemmy.today
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        8 months ago

        Well my dad is pushing 80 and has been smoking weed since the 60s. I’m not super concerned.

      • lolcatnip@reddthat.com
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        8 months ago

        Also “I don’t want to live forever” is a flawed argument for anything health related. People tend to imagine losing years from the end of their life when they’re already old and likely to be in poor health, but what happens more often in practice is that people lose years of being healthy.

    • sock@lemmy.world
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      8 months ago

      yeah pot might be a bit bad but its probably as bad as sugar and caffeine tbh

      shit keeps getting studies and it keeps being harmless

      sugar is literally legal cocaine its made the same way and produces the same effects and even looks the same, yet it tastes good so we cant regulate it.(or even honestly say how much is in our products in the US, EU nutrition facts r nice)

      • HuddaBudda@kbin.social
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        8 months ago

        Interesting.

        However the article alludes to two things.

        The age range for this study was 65 and older. That has to be taken with a grain of salt, most of these people are not as fit as they used to be.

        Even after controlling for smoking, elderly cannabis users having CVD risk had 20% more MACCE events encountered than non-users. Cannabis use in older non-smokers deserves investigation into CVD. risks

        However, the study doesn’t show any evidence of increased failure among people who smoke monthly or weekly, but on those who smoke daily. Which also might by synonymous with substance abuse. Which the author alludes to but does make a mention of.

        That being said, this article doesn’t really go in depth and a lot of information is hidden on the surface. I would love to deep dive into the main article research paper if you have it. Because there does seem to be a few pieces of the puzzle are missing.

        • treefrog@lemm.ee
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          8 months ago

          Could be that they’re not measuring substance abuse but the viability of smoked weed as a pain medication in people over 65.

          My dad has heart and lung issues and I encouraged him to quit smoking and be mindful with the edibles. THC does bind to receptors in the heart and it is concerning with his health, regardless of consumption method.

          CBD is relatively safe but can have drug interactions too because of liver substrate inhibition preventing other medication from being metabolized.

          A lot of reasons to not assume weed is safe in 65 year olds who often eat a handful of other meds every day.

  • Ulrich_the_Old@lemmy.ca
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    8 months ago

    As a person who has used pretty much daily since 1966 and who knows many others who have done the same it has not been my experience that people are having ANY health issues due to the use of cannabis. I spend my summers with a bunch of ancient musicians. We drink alcohol, smoke pot and play music most if not all are in good health and mentally capable. We are all in our 70s and 80s. Every year we lose someone but we have not been blaming cannabis for people dying in their 80s.

    • girlfreddy@lemmy.ca
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      8 months ago

      That’s fair.

      The other side of the coin is my ex-husband who rolled 14 joints every morning to take to work … and he smoked every one of them by himself.

      There are people who are addicted, sometimes because of massive trauma they faced as a child/youth.

      It would be unethical to disregard a study that simply disagrees with your personal preference or experience.

      • Ulrich_the_Old@lemmy.ca
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        8 months ago

        I do not see this as the other side of the coin. I have been using pretty much daily since 1966 except for a 3 week tolerance break once a year. I use much more than your ex and have never considered myself an addict as cannabis is not in any way addictive. I have zero trouble quitting for 3 weeks every year.

  • Melody Fwygon@lemmy.one
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    8 months ago

    Just by doing a little sleuthing I found out some things that really point to this article being a bit more flawed than one might think.

    From: https://themessenger.com/info/about-us

    The Messenger launched in May 2023. It is owned by JAF Communications, Inc., a privately-owned American digital media company based in West Palm Beach with additional offices in New York and Washington, D.C. The company was founded by James Finkelstein, Chairman and CEO.

    First; the news outlet breaking this story? It’s new. Brand Spanking New. So new that not even Wikipedia would recognize this site as notable.

    The Messenger was founded to champion balanced journalism in an era of bias, subjectivity, and misinformation. The Messenger offers thorough, objective, non-partisan, and timely news coverage of politics, business, health, technology, international affairs, sports, travel, and more.

    A noble ethos; but they really haven’t been around long enough to be able to assign a lean to their content yet. I think this is telling of their goals…to publish articles on topics that they feel are getting biased coverage.

    From: https://professional.heart.org/en/meetings/scientific-sessions

    Scientific Sessions 2023

    Pre-Sessions Symposia & Early Career Day: November 10, 2023

    Scientific Sessions: November 11–13, 2023

    Hmm…

    From the article: https://themessenger.com/health/marijuana-use-heart-attack-heart-failure-brain-issues

    Published 11/06/23 09:08 PM ET|Updated 11/06/23 09:08 PM ET

    HMMMMMmmmmm…

    Yeah these dates don’t match; and the author clearly did not attend this symposium to ask questions or do appropriate research on the matter.

    From: https://www.eurekalert.org/news-releases/1006523 (Emphasis added)

    In a secondary analysis, when coronary artery disease was added to the investigation, the risk of heart failure dropped from 34% to 27%, suggesting that coronary artery disease is a pathway through which daily marijuana use may lead to heart failure.

    Hmmm. I’m beginning to suspect this study is still kind of a pre-print and it’s not yet fully finished. Not to mention the issue that this is from a news release and lots of paraphrasing is probably at play here. If I’m understanding this correctly; the primary investigation did not even consider or take into account the effects of coronary artery disease nor would it appear that the study was crafted to screen for or account with people who already have coronary artery disease or similar problems or risk factors.

    “Our results should encourage more researchers to study the use of marijuana to better understand its health implications, especially on cardiovascular risk,” Bene-Alhasan said. “We want to provide the population with high-quality information on marijuana use and to help inform policy decisions at the state level, to educate patients and to guide health care professionals.”

    Hmmmmm. Do we have a bit of an agenda maybe? It’s hard to say for certain; but it sounds like they actually do want to cast doubt on the issue with relatively weak scientific evidence.

    The median participant age was 54 years; 60.9% of participants were female at birth; 70.7% self-identified as white adults; 21.8% were Black or African American adults; 4.2% were Asian adults; 2.2% were identified as more than one race/ethnicity; and 1.1% were from other races/ethnicities.

    I see. So we have an outsized number of older participants; who are far more likely to be at risk for heart problems.

    The study enrollment began in June 2016. Participants were followed from when they enrolled until June 2022, a maximum of approximately 4 years (45 months).

    Ah. Yeah. If we have been paying attention to the four year period between 2016 and 2022, we note that had a pandemic during that period too; which I suspect might also be problematic.

    In a second study, different researchers evaluated data from the 2019 National Inpatient Sample, the largest nationwide database of hospitalizations, to investigate whether hospital stays were complicated by a cardiovascular event, including heart attack, stroke, cardiac arrest or arrhythmia in patients who used marijuana. Researchers extracted records on adults older than age 65 years with cardiovascular risk factors who reported no tobacco use (cigarettes or other tobacco products). This group of patient records were then divided into two groups: marijuana users and non-marijuana users. The marijuana user’s hospital records were coded for cannabis use disorder which can vary from hospital to hospital.

    Yep. Older adults. It feels like they carefully selected subjects and data that would support their conclusions. Obviously this was Not a randomized controlled trial, and it should not be treated like one.